Identification of bovine doppel protein in testis, ovary and ejaculated spermatozoa
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چکیده
منابع مشابه
Identification of bovine doppel protein in testis, ovary and ejaculated spermatozoa.
Doppel (Dpl) protein is a recently identified prion-like protein. Although Dpl might be expressed in the brain after prion gene deletion, in both human and mice Dpl is normally expressed only in testis and spermatozoa, where it appears to be involved in male fertility. Little information is available so far about the expression pattern of Dpl in bovines, thus, hampering possible research on the...
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A hallmark of prion diseases or transmissible spongiform encephalopaties is the conversion of the cellular prion protein (PrP(C)), expressed by the prion gene (prnp), into an abnormally folded isoform (PrP(Sc)) with amyloid-like features that causes scrapie in sheep among other diseases. prnp together with prnd (which encodes a prion-like protein designated as Doppel), and prnt (that encodes th...
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ژورنال
عنوان ژورنال: Theriogenology
سال: 2005
ISSN: 0093-691X
DOI: 10.1016/j.theriogenology.2004.06.009